A force field for energy calculations and protein design

Description of FoldX versions

Version 3.0 beta3

  • Correction of a bug in PositionScan.
    When doing single point mutations with PositionScan, there was a problem of one-letter/three-letter code translation.
  • We recommend using BuildModel for mutation

Version 3.0 beta2

  • Coorrection of the implementation of water molecules inside the force field
    You can now read and take into account crystal waters or even predict the important water bridges.
  • Change in the headers for some energy outputs
  • Correction of a bug when mutating a residue from a Cysteine to anything else where the clashes were not correctly computed

Version 3.0 beta

  • Optimization of sidechain positions
  • "Repairing" pdb files
  • Full mutation capabilities (both Protein and DNA) with backbone fixed